IRRITABLE BOWEL SYNDROME (IBS) AND A LOW FODMAP DIET: CURRENT APPROACHES AND CLINICAL FINDINGS

https://doi.org/10.71284/tjmhs.2026325

Özet

Irritable bowel syndrome (IBS) is a chronic, relapsing functional gastrointestinal disorder characterized by ab
dominal pain, bloating, and altered bowel habits in the absence of identifiable organic disease. It is considered
a multifactorial condition within the biopsychosocial model and significantly impairs quality of life.
Current evidence indicates that IBS pathophysiology involves altered gut motility, visceral hypersensitivity,
changes in gut microbiota, increased intestinal permeability, and dysregulation of the gut–brain axis. Among
dietary interventions, the low-FODMAP diet has emerged as an effective strategy for symptom management,
although potential long-term effects such as microbiota alterations and nutrient deficiencies have been reported.
Psychological factors may influence symptom severity and treatment response. Therefore, integrating psycho
logical interventions such as cognitive behavioral therapy and stress management with dietary approaches is
recommended. Recent evidence suggests that multidisciplinary management strategies provide superior out
comes in symptom control and quality of life.
Keywords: Irritable bowel syndrome, low FODMAP diet, gut–brain axis, microbiota, multidisciplinary man
agement